Coventry University | Dr. Helen Maddock

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Dr. Helen Maddock

Theme Lead

My Research Vision

The objective of my research is the understanding of the disease process and the intracellular signal transduction mechanisms and cellular stress responses that lead to cardiac contractile dysfunction and myocardial injury aligned to diabetes, heart failure and drug induced cardiotoxicity, with an aim to provide a rational basis for prevention or therapeutic intervention, including the involvement of biomarker identification. I have been instrumental in investigating the impact of mitochondrial function aligned to cardiovascular cellular stress responses, as evidenced by my publications. In addition I am currently in the process of exploiting the commercial aspect of my research and I have filed several priority patents to support the formation of the university spin-out company - InoCardia.


My research outputs in the cardiovascular area include over 41 peer-reviewed publications (full papers, book chapter and abstracts). My research was returned in the RAE UoA12 assessment within the Allied Health Professionals submission. I review grants for a variety of funding bodies including Wellcome Trust, MRC and BHF and prolific MSc and PhD examiners, as well being responsible for editing the British Society for Cardiovascular Research Journal Bulletin. 

I have given invited talks about my research to both national and international academic audiences and within industry, and have given interviews on BBC radio about science-related issues. I have experience of establishing strong collaborative partnerships with basic science, clinical and industry colleagues at UHCW, Birmingham Children’s Hospital, UCL, Glostrup University Hospital, University of Cape Town, Covance and World Precision Instruments, to name but a few examples, in order to enable the translation of our teams pre-clinical cardiovascular research findings into a clinical and commercial setting. In order to progress research at Coventry University I am committed to concentrating on building and developing the academic and commercial research in the area of cardiovascular biology, supported by the world leading external collaborators from academia and industry.


Research breakout image

Principal Lecturer in Cardiovascular Physiology and Pharmacology

Building: James Starley
Room: JS139
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